Description:
Reviews:
5.0 out of 5 stars A reliable source for a molecule showing real potential in animal studies, w human studies to come
These guys are gaining a good reputation and so I decided to purchase from them rather than the usual vendor I use because their price was lower and the quality seems just as good.Spermidine is a natural polyamine that animal studies have shown stimulates autophagy, a process that recycles cellular components and may have anti-aging effects. Spermidine levels decline with aging, and some studies suggest that increasing spermidine intake with food or supplements may improve health and longevity.However, there are very few human studies using spermidine 10 milligrams as a supplement. I found only one clinical trial that used this dose in 100 older adults for 90 days to test its effect on memory and cognitive decline. The results were not very impressive, as there was no significant difference between the spermidine group and the placebo group on any of the cognitive tests.Another clinical trial is currently recruiting participants to test the metabolic responses to spermidine supplementation at doses of 5 or 10 milligrams per day for 12 weeks.The aim is to measure changes in biomarkers related to inflammation, oxidative stress, mitochondrial function, autophagy and aging.Therefore, it seems that more research is needed to establish the optimal dose and duration of spermidine supplementation for humans, as well as its safety and efficacy for various health outcomes. But there is a lot of interest from legitimate researchers, because the non-human studies look so promising. It's typical that the early studies on mice don't directly translate, but there wouldn't be a lot of activity researching the potential if there wasn't real evidence that there is real potential! Stay healthy, stay safe, take care.
5.0 out of 5 stars Good for your longevity
Great supplement, lot of health benefits..
5.0 out of 5 stars Very good product
Very good product
5.0 out of 5 stars It’s working
I think it’s working well, i do complex with other supplements, so hard to say which one affects more)) but now i feel better than before
4.0 out of 5 stars I noticed a difference in my skin in one week
This works but I really want to know how much actual spermidine is in this product. I have used DoNotAge.orgs spermidine and this one and they both are very effective as far as the difference I see. With both of these products I see my skin firming and wrinkles minimizing within a week, literally. I have a question about the actual amount of spermidine in these spermidine capsules. The question I have is too long to post in the questions segment..so I will post it in a review: I have been taking these for a while now and I like them but I wanted to get some information so I could get an accurate idea of how much spermidine is in each capsule. I emailed the company this information: Please let me know if the below is correct regarding amount of spermidine per 2 capsule serving:From what I understand, it looks like the product you have in your capsules is spermidine trihydrochloride which has a chemical formula of: C7H19N3·3HCl and a molecular weight of 254.63 g/mol. Spermidine has a chemical formula of C7H19N3 and has a molecular weight of 145.2459 g/mol. So for any given amount of Spermidine HCL, the actual weight of the spermidine is only going to be 57% and the remaining 43% weight is due to the 3HCL. So this would lead me to believe that since you have 10mg of Spermidine HCL in each serving, that the actual amount of spermidine in each 2 capsules is only 5.7mg and the amount of the 3HCL is 4.3mg. Is this correct? If this is the case, it would be very helpful if you could list the actual amount of spermidine in your capsules, instead of just listing the weight for the spermidine 3HCL. Since the actual amount of spermidine found in spermidine 3HCL is only 57% or 5.7mg per every 10mg
5.0 out of 5 stars Stopped hair from falling out
I had headaches when I started this, so I backed the dosage down to only one per day instead of two. That was still a little bit strong, so I was taking them every other day. Eventually I could take 1 10mg per day. When I got to the end of the bottle, I wasn’t sure if I had had any results? I am retirement age and felt like my skin may or may not have looked better. After a couple of weeks, I realized when I brushed my hair, I no longer had a brush full of hair. Then I realized when I vacuum, I no longer have to clean all of my hair out of the brush each time. My hairline was starting to get sparse and after taking an entire bottle, I could see baby hairs is growing back. Ordered another bottle and will report back if I noticed other great results.
3.0 out of 5 stars capsules are not filled fully and some are empty
Some of the capsules are .25 - .5 empty.
1.0 out of 5 stars Not GF
I took this supplement for two weeks and couldn’t figure out why I had diarrhea every day. I now realize why. I had to throw this in the garbage.
item as described
product arrived on time.
Buen producto, un poco alto de precio
Buen producto, un poco alto de precio
تحت التجربه
تحت التجربه
منتج ليس هو الذي طلبته
المنتج متغير أريد ارجاعه ولا يوجد إرجاع
How can you tell if it works?
No difference after 4 weeks. Not sure how you gauge effectiveness.
Visit the Double Wood Supplements Store
Spermidine Supplement (10mg of 99% Spermidine 3HCL - Third Party Tested) 120 Capsules - Over 100x More Potent Than Wheat Germ Extract for Cell Membrane, Telomere Health and Aging by Double Wood
AED24460
Quantity:
Order today to get by 7-14 business days
This item qualifies for free delivery
Imported From: United States
At BOLO, we work hard to ensure the products you receive are new, genuine, and sourced from reputable suppliers.
BOLO is not an authorized or official retailer for most brands, nor are we affiliated with manufacturers unless specifically stated on a product page. Instead, we source verified sellers, authorized distributors or directly from the manufacturer.
Each product undergoes thorough inspection and verification at our consolidation and fulfilment centers to ensure it meets our strict authenticity and quality standards before being shipped and delivered to you.
If you ever have concerns regarding the authenticity of a product purchased from us, please contact Bolo Support. We will review your inquiry promptly and, if necessary, provide documentation verifying authenticity or offer a suitable resolution.
Your trust is our top priority, and we are committed to maintaining transparency and integrity in every transaction.
All product information, images, descriptions, and reviews originate from the manufacturer or from trusted sellers overseas. BOLO is not affiliated with, endorsed by, or an authorized retailer for most brands listed on our website unless stated otherwise.
While we strive to display accurate information, variations in packaging, labeling, instructions, or formulation may occasionally occur due to regional differences or supplier updates. For detailed or manufacturer-specific information, please contact the brand directly or reach out to BOLO Support for assistance.
Unless otherwise stated, all prices displayed on the product page include applicable taxes and import duties.
BOLO operates in accordance with the laws and regulations of United Arab Emirates. Any items found to be restricted or prohibited for sale within the UAE will be cancelled prior to shipment. We take proactive measures to ensure that only products permitted for sale in United Arab Emirates are listed on our website.
All items are shipped by air, and any products classified as “Dangerous Goods (DG)” under IATA regulations will be removed from the order and cancelled.
All orders are processed manually, and we make every effort to process them promptly once confirmed. Products cancelled due to the above reasons will be permanently removed from listings across the website.
Similar suggestions by Bolo
More from this brand
Similar items from “Blended Vitamin & Mineral Supplements”
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Or share with link
https://www.bolo.ae/products/UO09AC4ZCDO
Visit the Double Wood Supplements Store
Spermidine Supplement (10mg of 99% Spermidine 3HCL - Third Party Tested) 120 Capsules - Over 100x More Potent Than Wheat Germ Extract for Cell Membrane, Telomere Health and Aging by Double Wood
AED24460
Quantity:
Order today to get by 7-14 business days
This item qualifies for free delivery
Imported From: United States
At BOLO, we work hard to ensure the products you receive are new, genuine, and sourced from reputable suppliers.
BOLO is not an authorized or official retailer for most brands, nor are we affiliated with manufacturers unless specifically stated on a product page. Instead, we source verified sellers, authorized distributors or directly from the manufacturer.
Each product undergoes thorough inspection and verification at our consolidation and fulfilment centers to ensure it meets our strict authenticity and quality standards before being shipped and delivered to you.
If you ever have concerns regarding the authenticity of a product purchased from us, please contact Bolo Support. We will review your inquiry promptly and, if necessary, provide documentation verifying authenticity or offer a suitable resolution.
Your trust is our top priority, and we are committed to maintaining transparency and integrity in every transaction.
All product information, images, descriptions, and reviews originate from the manufacturer or from trusted sellers overseas. BOLO is not affiliated with, endorsed by, or an authorized retailer for most brands listed on our website unless stated otherwise.
While we strive to display accurate information, variations in packaging, labeling, instructions, or formulation may occasionally occur due to regional differences or supplier updates. For detailed or manufacturer-specific information, please contact the brand directly or reach out to BOLO Support for assistance.
Unless otherwise stated, all prices displayed on the product page include applicable taxes and import duties.
BOLO operates in accordance with the laws and regulations of United Arab Emirates. Any items found to be restricted or prohibited for sale within the UAE will be cancelled prior to shipment. We take proactive measures to ensure that only products permitted for sale in United Arab Emirates are listed on our website.
All items are shipped by air, and any products classified as “Dangerous Goods (DG)” under IATA regulations will be removed from the order and cancelled.
All orders are processed manually, and we make every effort to process them promptly once confirmed. Products cancelled due to the above reasons will be permanently removed from listings across the website.
Description:
Reviews:
5.0 out of 5 stars A reliable source for a molecule showing real potential in animal studies, w human studies to come
These guys are gaining a good reputation and so I decided to purchase from them rather than the usual vendor I use because their price was lower and the quality seems just as good.Spermidine is a natural polyamine that animal studies have shown stimulates autophagy, a process that recycles cellular components and may have anti-aging effects. Spermidine levels decline with aging, and some studies suggest that increasing spermidine intake with food or supplements may improve health and longevity.However, there are very few human studies using spermidine 10 milligrams as a supplement. I found only one clinical trial that used this dose in 100 older adults for 90 days to test its effect on memory and cognitive decline. The results were not very impressive, as there was no significant difference between the spermidine group and the placebo group on any of the cognitive tests.Another clinical trial is currently recruiting participants to test the metabolic responses to spermidine supplementation at doses of 5 or 10 milligrams per day for 12 weeks.The aim is to measure changes in biomarkers related to inflammation, oxidative stress, mitochondrial function, autophagy and aging.Therefore, it seems that more research is needed to establish the optimal dose and duration of spermidine supplementation for humans, as well as its safety and efficacy for various health outcomes. But there is a lot of interest from legitimate researchers, because the non-human studies look so promising. It's typical that the early studies on mice don't directly translate, but there wouldn't be a lot of activity researching the potential if there wasn't real evidence that there is real potential! Stay healthy, stay safe, take care.
5.0 out of 5 stars Good for your longevity
Great supplement, lot of health benefits..
5.0 out of 5 stars Very good product
Very good product
5.0 out of 5 stars It’s working
I think it’s working well, i do complex with other supplements, so hard to say which one affects more)) but now i feel better than before
4.0 out of 5 stars I noticed a difference in my skin in one week
This works but I really want to know how much actual spermidine is in this product. I have used DoNotAge.orgs spermidine and this one and they both are very effective as far as the difference I see. With both of these products I see my skin firming and wrinkles minimizing within a week, literally. I have a question about the actual amount of spermidine in these spermidine capsules. The question I have is too long to post in the questions segment..so I will post it in a review: I have been taking these for a while now and I like them but I wanted to get some information so I could get an accurate idea of how much spermidine is in each capsule. I emailed the company this information: Please let me know if the below is correct regarding amount of spermidine per 2 capsule serving:From what I understand, it looks like the product you have in your capsules is spermidine trihydrochloride which has a chemical formula of: C7H19N3·3HCl and a molecular weight of 254.63 g/mol. Spermidine has a chemical formula of C7H19N3 and has a molecular weight of 145.2459 g/mol. So for any given amount of Spermidine HCL, the actual weight of the spermidine is only going to be 57% and the remaining 43% weight is due to the 3HCL. So this would lead me to believe that since you have 10mg of Spermidine HCL in each serving, that the actual amount of spermidine in each 2 capsules is only 5.7mg and the amount of the 3HCL is 4.3mg. Is this correct? If this is the case, it would be very helpful if you could list the actual amount of spermidine in your capsules, instead of just listing the weight for the spermidine 3HCL. Since the actual amount of spermidine found in spermidine 3HCL is only 57% or 5.7mg per every 10mg
5.0 out of 5 stars Stopped hair from falling out
I had headaches when I started this, so I backed the dosage down to only one per day instead of two. That was still a little bit strong, so I was taking them every other day. Eventually I could take 1 10mg per day. When I got to the end of the bottle, I wasn’t sure if I had had any results? I am retirement age and felt like my skin may or may not have looked better. After a couple of weeks, I realized when I brushed my hair, I no longer had a brush full of hair. Then I realized when I vacuum, I no longer have to clean all of my hair out of the brush each time. My hairline was starting to get sparse and after taking an entire bottle, I could see baby hairs is growing back. Ordered another bottle and will report back if I noticed other great results.
3.0 out of 5 stars capsules are not filled fully and some are empty
Some of the capsules are .25 - .5 empty.
1.0 out of 5 stars Not GF
I took this supplement for two weeks and couldn’t figure out why I had diarrhea every day. I now realize why. I had to throw this in the garbage.
item as described
product arrived on time.
Buen producto, un poco alto de precio
Buen producto, un poco alto de precio
تحت التجربه
تحت التجربه
منتج ليس هو الذي طلبته
المنتج متغير أريد ارجاعه ولا يوجد إرجاع
How can you tell if it works?
No difference after 4 weeks. Not sure how you gauge effectiveness.
Similar suggestions by Bolo
More from this brand
Similar items from “Blended Vitamin & Mineral Supplements”
Share with
Or share with link
https://www.bolo.ae/products/UO09AC4ZCDO