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Age Later: Health Span, Life Span, and the New Science of Longevity

Description:

How do some people avoid the slowing down, deteriorating, and weakening that plagues many of their peers decades earlier? Are they just lucky? Or do they know something the rest of us don’t? Is it possible to grow older without getting sicker? What if you could look and feel fifty through your eighties and nineties?

Founder of the Institute for Aging Research at the Albert Einstein College of Medicine and one of the leading pioneers of longevity research, Dr. Nir Barzilai’s life’s work is tackling the challenges of aging to delay and prevent the onset of all age-related diseases including “the big four”: diabetes, cancer, heart disease, and Alzheimer’s.

One of Dr. Barzilai’s most fascinating studies features volunteers that include 750 SuperAgers―individuals who maintain active lives well into their nineties and even beyond―and, more importantly, who reached that ripe old age never having experienced cardiovascular disease, cancer, diabetes, or cognitive decline.

In
Age Later, Dr. Barzilai reveals the secrets his team has unlocked about SuperAgers and the scientific discoveries that show we can mimic some of their natural resistance to the aging process. This eye-opening and inspirational book will help you think of aging not as a certainty, but as a phenomenon―like many other diseases and misfortunes―that can be targeted, improved, and even cured.


Editorial Reviews

Review

"A thoughtful take on aging that should be of interest to all concerned with the overlap between health and aging." ―Library Journal

“In this technical but promising book, Barzilai scrutinizes the lives of centenarians to find the key factors behind their healthy longevity. Readers who enjoy learning the science behind medical theories will be fascinated.”
Booklist

“Dr. Barzilai is the only person in the world who could have written this remarkable book. Not only is he a world leader in aging research, but also happens to be one of the best science communicators on the planet. Age Later will change how you think about your own life. It is easy to read, humorous, and hard to put down. I highly recommend it!"
―David A. Sinclair, PhD, bestselling author,
Lifespan: Why We Age?and Why We Don't Have to

“Many of us have been waiting for this excellent book on longevity by Dr. Nir Barzilai. Nir is one of the international leaders in the aging field and
Age Later is a tour de force, compressing thirty years of top research by his group and others into an easy-to-read story on how to stay young for as long as possible.”
―Valter D. Longo, PhD, bestselling author of
The Longevity Diet

About the Author

NIR BARZILAI, M.D., is the founding Director of the Institute for Aging Research at Albert Einstein College of Medicine and the Nathan Shock Center for Excellence in the Basic Biology of Aging and the Einstein Glenn Center for the Biology of Human Aging. He is also the Scientific Director of the American Federation for Aging Research (AFAR). Dr. Barzilai discovered the first longevity gene in humans and has since discovered several others, and he is the co-founder of CohBar, a clinical stage biotechnology company focused on increasing health span by developing treatments for age-related diseases. Age Later is his first publication for consumers.

Reviews:

5.0 out of 5 stars Disrupting aging

j.v. · August 9, 2020

To say that mortality has always been something to avoid is an understatement. In the evolutionary history of life delaying mortality must have been a powerful selectable trait. Delaying mortality is something not all species are equally good at. For example, while bowhead whales can live for over 200 years, our most favorite experimental animal, the mouse, cannot expect to live longer than about 3 years, and that is under optimal conditions in our animal facilities. In the wild they usually die around 8 months, from cold, lack of food or predation. Humans soon found out that even in the best of times mortality was a given. Especially the rich and powerful had a problem with that, which explains that so many kings and emperors tried their utmost to gain immortality. Since then humans never stopped trying to find ways to ward off death from old age and even now there are plenty of aggressively advertised interventions to save us from aging. Alas, the far majority of such interventions are far from the realm of regular medicine and can better be avoided.But very recently something changed in anti-aging medicine and this time it came not from charlatans but from serious scientists. This is not obvious because regular science for quite a long time expressed no interest in research on aging, which was considered the exclusive domain of charlatans. What happened and led serious scientists change their mind was the discovery that aging, like a disease, could be targeted for intervention. Not for gaining immortality but for increasing the health span of life. This is the topic of the book Age Later, Health Span, Life Span, and the New Science of Longevity by Nir Barzilai. Nir is a friend and colleague of mine and I know him for a long time. His new book describes the promise of the new science of aging in a lighthearted, entertaining style, but with all the facts in good order and narrated so clearly that also the non-scientist will be able to follow the main concepts presented.The book is focused on the recently emerged new field of “Geroscience”, the study of aging at the interface of its basic biological principles and the diseases it will cause late in life. Why is this an important book? The main problem investigators who study aging have always experienced is the lack of practical appeal of the science of aging and therefore very limited funding. This is primarily based on vested interest. The established behemoths of medical research, cancer, cardiovascular disease, diabetes, have incentives to block a switch to a different universe where individual diseases are no longer the be-all and end-all of medicine. That is, until Geroscience came along. As described in the book, the main impact of Geroscience is to once and for all put the lie to the idea that aging is inevitable and cannot be targeted for medical intervention. This book, for example, does that very effectively in Chapter 7, Making Eighty the New Sixty, providing a lucid description of where we can go from here based on the stream of new, convincing scientific data that interventions in aging are possible and will have a major impact on prevention and treatment of chronic disease. It should open the eyes of politicians, investors and the medical establishment to a new world that is coming.One way to turn Geroscience into the disruptive technology that it could be is to make people understand that things do not need to be the way they are. That is, it should not be necessary to become increasingly fearful when approaching 60 and then 70 that one of the big diseases will catch you. Age Later is a manifesto to underscore a new future. A future where everybody will have access to medication that targets multiple chronic diseases simultaneously rather than one by one by targeting the basic mechanisms of aging that underlie all these diseases. This also makes economic sense. As described in Chapter 1, One Hundred Years Young, those who live to a hundred because they have the right genes suffer less and have many more years of healthy old age than the average human. However, also the health care costs of such a lucky individual are only a fraction of the health care costs of that average individual. As described further on in the book, the genomes of these slow agers have now become treasure troves for investigators interested in finding out how they do it. What are the genetic variants that dictate a healthy long live? If we would know that, we could use such genes as starting points to develop drugs that mimic these good genes so that also the far majority of humanity, which normally would have to do without, can still profit from them.Age Later does the job of providing all that critical information in a way that is clear to the non-scientist, convincing for investors and persuasive for politicians to make the necessary changes in the medical establishment. In this respect the story of the TAME trial in Chapter six, The Quest to Prove Aging can be Targeted, is critically important because it shows that it actually is possible to get at least some of the regulators on your side.The book is well organized with a number of informative boxes to quickly outline specific scientific aspects important in following the reasoning. It ends, quite appropriately, with the future, in a Chapter called Bright Horizons that discusses some of the hottest areas of potential interventions. Overall a book to point the way as to how Geroscience is on its way to disrupt the medical sciences and change our future.

4.0 out of 5 stars Great book on health and secrets to anti-aging research!

A.T.D. · August 24, 2020

Great book on health and secrets to anti-aging research! I really enjoy this book as it got technical without being too overly technical. This is a great book to read in addition to David Sinclair’s lifespan. These are all things that everyone can do in the hopes of having a greater health span and a lifespan. Highly recommended!

5.0 out of 5 stars Well-written and comprehensive, but written several years ago.

A. · February 22, 2025

Written by an old friend & colleague, so I can't be totally objective. Well written and comprehensive, it's a little dated, since there have been lots of advances in the 5 years since it was published (and maybe an additional year since it was written). It's primarily based on extensive studies on "super-agers" - people who remain in good health ("healthspan" as opposed to "lifespan") into their 90's and beyond. A major takehome lesson is to choose long-lived ancestors, and have your great-great grandparents cosign your mortgage.

3.0 out of 5 stars Informative but…

P. · March 3, 2024

While this tome provides many informative insights into innovations for improving and increasing health span and life span, some of the science is beyond a simple layman like me. Finally some of the anecdotes smack of academic and commerce driven name dropping.

5.0 out of 5 stars Great science humbly narrated!

M.J. · November 22, 2021

The beauty of science is to make things simple- and this is the essence of this book. Dr Barzilai is a world-class leading geroscientist who did a great service to the public by relaying the complexities of geroscience in a very straightforward and engaging language. The book is a fascinating exploration of the most exciting current research in the field of ageing and longevity. The humble and enticing narration of the scientific facts often adorned with witty rhetorics makes the book exceptionally enjoyable to read.The book not only explores different aspects of ageing research but also narrates the fascinating journey of groundbreaking research led by Professor Barzilai at Albert Einstein College of Medicine. Chapters three to eight cover different hallmarks of ageing and introduce the novel discoveries- and ongoing efforts- in the pharmaceutical front to stop ageing.This book is truly a "must-read" for both the experts and the general audience alike.

5.0 out of 5 stars Interesting as a followup to David Sinclair's "Span" book

Z. · October 29, 2021

The book speaks about the research for how to add years of healthy life, to life, but it mainly is not a recommendations book. It definitely has less recommendations that his collegue's book Span. It is more about the research and development. The hopes, the obstacles, etc. It though has a chapter on recommendation, where he mentions some of the recommendations made by Sinclair. It is interesting to see both how careful you should be in research, and how the money makes an issue.

4.0 out of 5 stars Feels like you read a family story not a science

A. · June 26, 2023

I would say it’s close to nun practical tool u can use or understand from this book. Not saying it’s bad, but it’s more like a common language translation of Mr Barzilay research.

5.0 out of 5 stars Fantastic book on LONGEVITY "know how"!

S. · March 14, 2023

Fascinating concepts on what "TO DO" to live longer. Well written book - easy to read!

interesting, scientific work

A.C. · November 17, 2024

An excellent introduction to recent advances in gerontology in the tradition of Sinclair, Attia and Fung. Interesting personal views of science research by one of the most prolific scientists. Has a few commercially self-interested points but does not try to sell you anything. Well referenced and more scientific than most of the books in this field. Worth your time.

Excellent combination of science and stories.

M. · March 4, 2022

Excellent book, really enjoyed the writing style. Weaved a lot of hard science / facts with stories of fascinating people that lived to >100. Will do a chapter by chapter overview for the Age Well Times. I rarely give 5 stars, this one deserves it!

Keine Tipps

N. · November 30, 2022

Keine Tipps, aber endlose Stories über irgendwelche Leute und den Autor.Nicht zu empfehlen. Sehr schade ums Geld.

This is an easy read - everyone should read by age 50!

s. · January 20, 2021

This is the information I wanted - I will probably live to 105 and I want to do it healthy and this has the latest research presented in an understandable manner. Light and humorous I'm not a scientist but a retired nurse and at 82 I don't want to have any more pain than is necessary and I'm in good health and want to stay there - this is my guide! I have just finished it, have notes on how to change my lifestyle a little. So good to know how to balance my diet and I'm happy the author admits he's fluffy - I am too, so I'm going to hold onto it! Read the book, I was smiling a lot. Thank you Dr. Nir. Sheilah B

Kind of good

K. · January 18, 2023

Much deeper information about the anty ageing stuff and information the book is interesting to be able to finish for 3 stars

Age Later: Health Span, Life Span, and the New Science of Longevity

Product ID: U1250230853
Condition: New

4.3

AED16546

Price includes VAT & Import Duties
Type: Hardcover
Availability: In Stock

Quantity:

|

Order today to get by 7-14 business days

Delivery fee of AED 20. Free for orders above AED 200.

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Imported From: United States

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Age Later: Health Span, Life Span, and the New Science of Longevity

Product ID: U1250230853
Condition: New

4.3

Age Later: Health Span, Life Span, and the New Science of Longevity-0
Type: Hardcover

AED16546

Price includes VAT & Import Duties
Availability: In Stock

Quantity:

|

Order today to get by 7-14 business days

Delivery fee of AED 20. Free for orders above AED 200.

Returns & Warranty policies

Imported From: United States

At BOLO, we work hard to ensure the products you receive are new, genuine, and sourced from reputable suppliers.

BOLO is not an authorized or official retailer for most brands, nor are we affiliated with manufacturers unless specifically stated on a product page. Instead, we source verified sellers, authorized distributors or directly from the manufacturer.

Each product undergoes thorough inspection and verification at our consolidation and fulfilment centers to ensure it meets our strict authenticity and quality standards before being shipped and delivered to you.

If you ever have concerns regarding the authenticity of a product purchased from us, please contact Bolo Support. We will review your inquiry promptly and, if necessary, provide documentation verifying authenticity or offer a suitable resolution.

Your trust is our top priority, and we are committed to maintaining transparency and integrity in every transaction.

All product information, images, descriptions, and reviews originate from the manufacturer or from trusted sellers overseas. BOLO is not affiliated with, endorsed by, or an authorized retailer for most brands listed on our website unless stated otherwise.

While we strive to display accurate information, variations in packaging, labeling, instructions, or formulation may occasionally occur due to regional differences or supplier updates. For detailed or manufacturer-specific information, please contact the brand directly or reach out to BOLO Support for assistance.

Unless otherwise stated, all prices displayed on the product page include applicable taxes and import duties.

BOLO operates in accordance with the laws and regulations of United Arab Emirates. Any items found to be restricted or prohibited for sale within the UAE will be cancelled prior to shipment. We take proactive measures to ensure that only products permitted for sale in United Arab Emirates are listed on our website.

All items are shipped by air, and any products classified as “Dangerous Goods (DG)” under IATA regulations will be removed from the order and cancelled.

All orders are processed manually, and we make every effort to process them promptly once confirmed. Products cancelled due to the above reasons will be permanently removed from listings across the website.

Description:

How do some people avoid the slowing down, deteriorating, and weakening that plagues many of their peers decades earlier? Are they just lucky? Or do they know something the rest of us don’t? Is it possible to grow older without getting sicker? What if you could look and feel fifty through your eighties and nineties?

Founder of the Institute for Aging Research at the Albert Einstein College of Medicine and one of the leading pioneers of longevity research, Dr. Nir Barzilai’s life’s work is tackling the challenges of aging to delay and prevent the onset of all age-related diseases including “the big four”: diabetes, cancer, heart disease, and Alzheimer’s.

One of Dr. Barzilai’s most fascinating studies features volunteers that include 750 SuperAgers―individuals who maintain active lives well into their nineties and even beyond―and, more importantly, who reached that ripe old age never having experienced cardiovascular disease, cancer, diabetes, or cognitive decline.

In
Age Later, Dr. Barzilai reveals the secrets his team has unlocked about SuperAgers and the scientific discoveries that show we can mimic some of their natural resistance to the aging process. This eye-opening and inspirational book will help you think of aging not as a certainty, but as a phenomenon―like many other diseases and misfortunes―that can be targeted, improved, and even cured.


Editorial Reviews

Review

"A thoughtful take on aging that should be of interest to all concerned with the overlap between health and aging." ―Library Journal

“In this technical but promising book, Barzilai scrutinizes the lives of centenarians to find the key factors behind their healthy longevity. Readers who enjoy learning the science behind medical theories will be fascinated.”
Booklist

“Dr. Barzilai is the only person in the world who could have written this remarkable book. Not only is he a world leader in aging research, but also happens to be one of the best science communicators on the planet. Age Later will change how you think about your own life. It is easy to read, humorous, and hard to put down. I highly recommend it!"
―David A. Sinclair, PhD, bestselling author,
Lifespan: Why We Age?and Why We Don't Have to

“Many of us have been waiting for this excellent book on longevity by Dr. Nir Barzilai. Nir is one of the international leaders in the aging field and
Age Later is a tour de force, compressing thirty years of top research by his group and others into an easy-to-read story on how to stay young for as long as possible.”
―Valter D. Longo, PhD, bestselling author of
The Longevity Diet

About the Author

NIR BARZILAI, M.D., is the founding Director of the Institute for Aging Research at Albert Einstein College of Medicine and the Nathan Shock Center for Excellence in the Basic Biology of Aging and the Einstein Glenn Center for the Biology of Human Aging. He is also the Scientific Director of the American Federation for Aging Research (AFAR). Dr. Barzilai discovered the first longevity gene in humans and has since discovered several others, and he is the co-founder of CohBar, a clinical stage biotechnology company focused on increasing health span by developing treatments for age-related diseases. Age Later is his first publication for consumers.

Reviews:

5.0 out of 5 stars Disrupting aging

j.v. · August 9, 2020

To say that mortality has always been something to avoid is an understatement. In the evolutionary history of life delaying mortality must have been a powerful selectable trait. Delaying mortality is something not all species are equally good at. For example, while bowhead whales can live for over 200 years, our most favorite experimental animal, the mouse, cannot expect to live longer than about 3 years, and that is under optimal conditions in our animal facilities. In the wild they usually die around 8 months, from cold, lack of food or predation. Humans soon found out that even in the best of times mortality was a given. Especially the rich and powerful had a problem with that, which explains that so many kings and emperors tried their utmost to gain immortality. Since then humans never stopped trying to find ways to ward off death from old age and even now there are plenty of aggressively advertised interventions to save us from aging. Alas, the far majority of such interventions are far from the realm of regular medicine and can better be avoided.But very recently something changed in anti-aging medicine and this time it came not from charlatans but from serious scientists. This is not obvious because regular science for quite a long time expressed no interest in research on aging, which was considered the exclusive domain of charlatans. What happened and led serious scientists change their mind was the discovery that aging, like a disease, could be targeted for intervention. Not for gaining immortality but for increasing the health span of life. This is the topic of the book Age Later, Health Span, Life Span, and the New Science of Longevity by Nir Barzilai. Nir is a friend and colleague of mine and I know him for a long time. His new book describes the promise of the new science of aging in a lighthearted, entertaining style, but with all the facts in good order and narrated so clearly that also the non-scientist will be able to follow the main concepts presented.The book is focused on the recently emerged new field of “Geroscience”, the study of aging at the interface of its basic biological principles and the diseases it will cause late in life. Why is this an important book? The main problem investigators who study aging have always experienced is the lack of practical appeal of the science of aging and therefore very limited funding. This is primarily based on vested interest. The established behemoths of medical research, cancer, cardiovascular disease, diabetes, have incentives to block a switch to a different universe where individual diseases are no longer the be-all and end-all of medicine. That is, until Geroscience came along. As described in the book, the main impact of Geroscience is to once and for all put the lie to the idea that aging is inevitable and cannot be targeted for medical intervention. This book, for example, does that very effectively in Chapter 7, Making Eighty the New Sixty, providing a lucid description of where we can go from here based on the stream of new, convincing scientific data that interventions in aging are possible and will have a major impact on prevention and treatment of chronic disease. It should open the eyes of politicians, investors and the medical establishment to a new world that is coming.One way to turn Geroscience into the disruptive technology that it could be is to make people understand that things do not need to be the way they are. That is, it should not be necessary to become increasingly fearful when approaching 60 and then 70 that one of the big diseases will catch you. Age Later is a manifesto to underscore a new future. A future where everybody will have access to medication that targets multiple chronic diseases simultaneously rather than one by one by targeting the basic mechanisms of aging that underlie all these diseases. This also makes economic sense. As described in Chapter 1, One Hundred Years Young, those who live to a hundred because they have the right genes suffer less and have many more years of healthy old age than the average human. However, also the health care costs of such a lucky individual are only a fraction of the health care costs of that average individual. As described further on in the book, the genomes of these slow agers have now become treasure troves for investigators interested in finding out how they do it. What are the genetic variants that dictate a healthy long live? If we would know that, we could use such genes as starting points to develop drugs that mimic these good genes so that also the far majority of humanity, which normally would have to do without, can still profit from them.Age Later does the job of providing all that critical information in a way that is clear to the non-scientist, convincing for investors and persuasive for politicians to make the necessary changes in the medical establishment. In this respect the story of the TAME trial in Chapter six, The Quest to Prove Aging can be Targeted, is critically important because it shows that it actually is possible to get at least some of the regulators on your side.The book is well organized with a number of informative boxes to quickly outline specific scientific aspects important in following the reasoning. It ends, quite appropriately, with the future, in a Chapter called Bright Horizons that discusses some of the hottest areas of potential interventions. Overall a book to point the way as to how Geroscience is on its way to disrupt the medical sciences and change our future.

4.0 out of 5 stars Great book on health and secrets to anti-aging research!

A.T.D. · August 24, 2020

Great book on health and secrets to anti-aging research! I really enjoy this book as it got technical without being too overly technical. This is a great book to read in addition to David Sinclair’s lifespan. These are all things that everyone can do in the hopes of having a greater health span and a lifespan. Highly recommended!

5.0 out of 5 stars Well-written and comprehensive, but written several years ago.

A. · February 22, 2025

Written by an old friend & colleague, so I can't be totally objective. Well written and comprehensive, it's a little dated, since there have been lots of advances in the 5 years since it was published (and maybe an additional year since it was written). It's primarily based on extensive studies on "super-agers" - people who remain in good health ("healthspan" as opposed to "lifespan") into their 90's and beyond. A major takehome lesson is to choose long-lived ancestors, and have your great-great grandparents cosign your mortgage.

3.0 out of 5 stars Informative but…

P. · March 3, 2024

While this tome provides many informative insights into innovations for improving and increasing health span and life span, some of the science is beyond a simple layman like me. Finally some of the anecdotes smack of academic and commerce driven name dropping.

5.0 out of 5 stars Great science humbly narrated!

M.J. · November 22, 2021

The beauty of science is to make things simple- and this is the essence of this book. Dr Barzilai is a world-class leading geroscientist who did a great service to the public by relaying the complexities of geroscience in a very straightforward and engaging language. The book is a fascinating exploration of the most exciting current research in the field of ageing and longevity. The humble and enticing narration of the scientific facts often adorned with witty rhetorics makes the book exceptionally enjoyable to read.The book not only explores different aspects of ageing research but also narrates the fascinating journey of groundbreaking research led by Professor Barzilai at Albert Einstein College of Medicine. Chapters three to eight cover different hallmarks of ageing and introduce the novel discoveries- and ongoing efforts- in the pharmaceutical front to stop ageing.This book is truly a "must-read" for both the experts and the general audience alike.

5.0 out of 5 stars Interesting as a followup to David Sinclair's "Span" book

Z. · October 29, 2021

The book speaks about the research for how to add years of healthy life, to life, but it mainly is not a recommendations book. It definitely has less recommendations that his collegue's book Span. It is more about the research and development. The hopes, the obstacles, etc. It though has a chapter on recommendation, where he mentions some of the recommendations made by Sinclair. It is interesting to see both how careful you should be in research, and how the money makes an issue.

4.0 out of 5 stars Feels like you read a family story not a science

A. · June 26, 2023

I would say it’s close to nun practical tool u can use or understand from this book. Not saying it’s bad, but it’s more like a common language translation of Mr Barzilay research.

5.0 out of 5 stars Fantastic book on LONGEVITY "know how"!

S. · March 14, 2023

Fascinating concepts on what "TO DO" to live longer. Well written book - easy to read!

interesting, scientific work

A.C. · November 17, 2024

An excellent introduction to recent advances in gerontology in the tradition of Sinclair, Attia and Fung. Interesting personal views of science research by one of the most prolific scientists. Has a few commercially self-interested points but does not try to sell you anything. Well referenced and more scientific than most of the books in this field. Worth your time.

Excellent combination of science and stories.

M. · March 4, 2022

Excellent book, really enjoyed the writing style. Weaved a lot of hard science / facts with stories of fascinating people that lived to >100. Will do a chapter by chapter overview for the Age Well Times. I rarely give 5 stars, this one deserves it!

Keine Tipps

N. · November 30, 2022

Keine Tipps, aber endlose Stories über irgendwelche Leute und den Autor.Nicht zu empfehlen. Sehr schade ums Geld.

This is an easy read - everyone should read by age 50!

s. · January 20, 2021

This is the information I wanted - I will probably live to 105 and I want to do it healthy and this has the latest research presented in an understandable manner. Light and humorous I'm not a scientist but a retired nurse and at 82 I don't want to have any more pain than is necessary and I'm in good health and want to stay there - this is my guide! I have just finished it, have notes on how to change my lifestyle a little. So good to know how to balance my diet and I'm happy the author admits he's fluffy - I am too, so I'm going to hold onto it! Read the book, I was smiling a lot. Thank you Dr. Nir. Sheilah B

Kind of good

K. · January 18, 2023

Much deeper information about the anty ageing stuff and information the book is interesting to be able to finish for 3 stars

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More from this brand

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