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Actin-based Motility: Cellular, Molecular and Physical Aspects

Description:

Since the discovery of actin by Straub in the 1950’s and the pioneering work of Oosawa on actin self-assembly in helical laments in the 1960’s, many books and conference proceedings have been published. As one of the most essential p- teins in life, essential for movement in organisms rangingfrom bacteria to higher eukaryotes, it is no surprise that actin has fascinated generations of scientists from many different elds. Actin can be considered as a “living treasure” of biology; the kinetics and thermodynamics of self-assembly, the dissipative nature of actin po- merization, the molecular interactions of monomeric and polymerized actin with regulators, the mechanical properties of actin gels, and more recently the force p- ducing motile and morphogenetic processes organized by the actin nanomachine in response to signaling, are all milestones in actin research. Discoveries that directly derive from and provide deeper insight into the fundamental properties of actin are constantly being made, making actin an ever appealing research molecule. At the same time, the explosion in new technologies and techniques in biological sciences has served to attract researchers from an expanding number of disciplines, to study actin. This book presents the latest developments of these new multiscale approaches of force and movement powered by self-assembly processes, with the hope to opening our perspectives on the many areas of actin-based motility research.
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From the Back Cover

This book presents the cellular, molecular and physical aspects of force and movement by the self-assembly of actin, one of the most abundant proteins found in cells, into cytoskeletal filaments. « Actin-based motile processes » are responsible for a large variety of motile activities such as chemotactic locomotion, embryonic and metastatic cell migration, wound healing, eukaryotic cytokinesis and bacterial plasmid segregation, endocytic and phagocytic activities, as well as morphogenetic processes including, axis patterning in early embryos, axonal growth in brain development, and the immune response and synaptic plasticity processes at the origin of learning and memory. The book describes how the recently undertaken multidisciplinary and multiscale approaches have explored the molecular and physical mechanisms at the origin of force and movement produced by actin self-assembly. The chosen topics show how advances have been made in the field of cell motility due to the progress in live cell imaging, light microscopy, improved resolution in the structure of large protein assemblies, the biochemical analysis and mathematical modeling of actin assembly dynamics and the development of nanotechnologies enabling us to measure forces in the range of pico- to nano-newtons produced by actin assemblies.

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Actin-based Motility: Cellular, Molecular and Physical Aspects

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AED91921

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Visit the Springer Store

Actin-based Motility: Cellular, Molecular and Physical Aspects

Product ID: K9048193001
Condition: New
Actin-based Motility: Cellular, Molecular and Physical Aspects-0
Type: Hardcover

AED91921

Price includes VAT & Import Duties
Availability: In Stock

Quantity:

|

Order today to get by 7-14 business days

This item qualifies for free delivery

Returns & Warranty policies

Imported From: United Kingdom

At BOLO, we work hard to ensure the products you receive are new, genuine, and sourced from reputable suppliers.

BOLO is not an authorized or official retailer for most brands, nor are we affiliated with manufacturers unless specifically stated on a product page. Instead, we source verified sellers, authorized distributors or directly from the manufacturer.

Each product undergoes thorough inspection and verification at our consolidation and fulfilment centers to ensure it meets our strict authenticity and quality standards before being shipped and delivered to you.

If you ever have concerns regarding the authenticity of a product purchased from us, please contact Bolo Support. We will review your inquiry promptly and, if necessary, provide documentation verifying authenticity or offer a suitable resolution.

Your trust is our top priority, and we are committed to maintaining transparency and integrity in every transaction.

All product information, images, descriptions, and reviews originate from the manufacturer or from trusted sellers overseas. BOLO is not affiliated with, endorsed by, or an authorized retailer for most brands listed on our website unless stated otherwise.

While we strive to display accurate information, variations in packaging, labeling, instructions, or formulation may occasionally occur due to regional differences or supplier updates. For detailed or manufacturer-specific information, please contact the brand directly or reach out to BOLO Support for assistance.

Unless otherwise stated, all prices displayed on the product page include applicable taxes and import duties.

BOLO operates in accordance with the laws and regulations of United Arab Emirates. Any items found to be restricted or prohibited for sale within the UAE will be cancelled prior to shipment. We take proactive measures to ensure that only products permitted for sale in United Arab Emirates are listed on our website.

All items are shipped by air, and any products classified as “Dangerous Goods (DG)” under IATA regulations will be removed from the order and cancelled.

All orders are processed manually, and we make every effort to process them promptly once confirmed. Products cancelled due to the above reasons will be permanently removed from listings across the website.

Description:

Since the discovery of actin by Straub in the 1950’s and the pioneering work of Oosawa on actin self-assembly in helical laments in the 1960’s, many books and conference proceedings have been published. As one of the most essential p- teins in life, essential for movement in organisms rangingfrom bacteria to higher eukaryotes, it is no surprise that actin has fascinated generations of scientists from many different elds. Actin can be considered as a “living treasure” of biology; the kinetics and thermodynamics of self-assembly, the dissipative nature of actin po- merization, the molecular interactions of monomeric and polymerized actin with regulators, the mechanical properties of actin gels, and more recently the force p- ducing motile and morphogenetic processes organized by the actin nanomachine in response to signaling, are all milestones in actin research. Discoveries that directly derive from and provide deeper insight into the fundamental properties of actin are constantly being made, making actin an ever appealing research molecule. At the same time, the explosion in new technologies and techniques in biological sciences has served to attract researchers from an expanding number of disciplines, to study actin. This book presents the latest developments of these new multiscale approaches of force and movement powered by self-assembly processes, with the hope to opening our perspectives on the many areas of actin-based motility research.
Read more

From the Back Cover

This book presents the cellular, molecular and physical aspects of force and movement by the self-assembly of actin, one of the most abundant proteins found in cells, into cytoskeletal filaments. « Actin-based motile processes » are responsible for a large variety of motile activities such as chemotactic locomotion, embryonic and metastatic cell migration, wound healing, eukaryotic cytokinesis and bacterial plasmid segregation, endocytic and phagocytic activities, as well as morphogenetic processes including, axis patterning in early embryos, axonal growth in brain development, and the immune response and synaptic plasticity processes at the origin of learning and memory. The book describes how the recently undertaken multidisciplinary and multiscale approaches have explored the molecular and physical mechanisms at the origin of force and movement produced by actin self-assembly. The chosen topics show how advances have been made in the field of cell motility due to the progress in live cell imaging, light microscopy, improved resolution in the structure of large protein assemblies, the biochemical analysis and mathematical modeling of actin assembly dynamics and the development of nanotechnologies enabling us to measure forces in the range of pico- to nano-newtons produced by actin assemblies.

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